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The schematically shown ribozyme (green) binds to the target RNA (blue) by base pairing and installs the methyl group (red flag) at a defined site of a selected adenine. The reaction product m1A is shown in the red circle.

On the track of evolution: a catalytically active RNA molecule that specifically attaches methyl groups to other RNAs – a research group from the University of Würzburg reports on this new discovery in "Nature".

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Artistic representation of human stomach cells infected with Helicobacter pylori, showing the special Hummingbird cell shape induced by the bacterium.

The most important pathogenicity factors of the gastric pathogen Helicobacter pylori are centrally regulated by a small RNA molecule, NikS. And this was not the only surprise that NikS provided.

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Photo of a Venus flytrap with an insect inside.

The carnivorous Venus flytrap snaps shut when a prey touches it twice within 30 seconds. In the journal Nature Plants researchers report on how this plant's short-term memory and counting system works.

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Two point mutations are responsible for the fact that arginine is found in the NFATc1 protein instead of the amino acid lysine. This exchange prevents sumoylation and makes the affected T cells less aggressive.

Minor changes in immune cells can significantly affect the immune response, scientists of the University of Würzburg have now discovered. Their findings could be relevant for stem cell therapy.

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Scientists from Würzburg are investigating immune cells in different tissues, here for example ILC2s (red) or T-cells (blue) in the lung (right) or in the mucosa of the small intestine (left).

Specialized immune cells settle permanently in tissues of the body and build “local task forces”. Wuerzburger scientists have recently discovered, how these cells can regenerate themselves and can adapt to the new environment.

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