RVZ News

This specific Index looks at the current state of biomedical science around the world and what its renaissance might mean for patients. In this context, the Rudolf Virchow Center was selected to write an article about ongoing research at our center.

RVZ research group leader Prof. Dr. Pedro Friedmann Angeli is again a Highly Cited Researcher. Their work is most frequently cited in publications of other scientists. Researchers from the University are therefore included in the Highly Cited Researchers 2022 List.

German President Frank-Walter Steinmeier has awarded the 26th German Future Prize to researchers from the Jena-based company Carl Zeiss Microscopy: Thomas Kalkbrenner, Jörg Siebenmorgen and Ralf Wolleschensky (10/26-22). The award winners have developed a novel microscope for the gentle 3-D imaging of living cells, which will enable further intensive research into the fundamentals of life. Fantastic news for the bioimaging research area and our speaker Prof. Markus Sauer, who was involved in the development of this award-winning ZEISS Lattice Lightsheet Microscopy technique.

Researchers at the Rudolf Virchow Center of the University of Würzburg have unveiled the crystal structures of UBA6 in complex with either ATP or the ubiquitin-like protein FAT10. These results provide the foundation to study the individual roles of UBA6 towards the attachment of either ubiquitin or FAT10 to target proteins and the downstream cellular pathways with possible implications for the etiology of certain tumors. This study was published in the journal Nature Communications.

Inhibitory synapses in neuron cultures and brain tissue can now be visualized with ease and with high contrast. The newly developed synthetic affinity probe Sylite can be applied both for widefield and confocal 3D volumetric synapse visualization, for in-tissue inhibitory circuits mapping and for super-resolution imaging of synapses.

We are inviting applications for a Group Leader (f/m/d) in Chemical Biology. The RVZ appoints group leaders early in their career and provides them with a supportive, collaborative environment and generous work package for their independent position. Significant core funding and limited teaching responsibilities will allow you to embark on a visionary research program.

Scientists from the University of Würzburg and the University of Strasbourg identified a new important molecular region in an essential human DNA repair complex, consisting of the proteins XPD and MAT1. This complex forms a central unit in the nucleotide excision DNA repair mechanism (NER) and thus protects our genetic information. The findings were published in the journal Nature Communications and could provide new starting points for cancer therapy.

Scientists from the University of Würzburg and the University of Freiburg succeeded in determining the complex molecular structure of the bacterial enzyme cytochrome bd oxidase. Since humans do not have this type of oxidase, this enzyme could be an interesting target for novel antibiotics.

For the foundation of the first two Dioscuri centers our RVZ group leader Dr. Grzegorz Sumara will return to Poland. The Grzegorz Sumara centre will focus on elucidating signalling pathways involved in metabolic diseases.

The 2019 Nature Index is an indicator of the high-quality research output in natural sciences and life sciences at the University of Würzburg which ranks 69th internationally and 4th in Germany.

Annual Report 2017-2018 of the Rudolf Virchow Center

Annual Report 2017-2018 of the Rudolf Virchow Center

Ten years ago the school laboratory of the German Rudolf Virchow Center was founded, where pupil get engaged in the current research of biomedicine. So far, 5,592 students have participated.

The German Cancer Aid will set up one of five Mildred Scheel Junior Research Centers in Würzburg. The center aims to provide ideal working conditions for young cancer researchers.